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Unformatted text preview: CH 3 COOH, 5C N H NO 2 Write resonance structures for the intermediate formed by attack at 2- and 3-positions of pyrrole. From the examination of the intermediates offer an explanation for the preferential nitration at the 2-position. 4. Treatment of benzene with succinic anhydride in the presence of a strong acid, such as phosphoric acid, gives the following -ketoacid. Propose a detailed stepwise mechanism for this reaction. Use curved arrows to indicate the flow of electrons. + O O O H 3 PO 4 OH O O 5. Write down the major product of each of the following reactions. Br O B O n-Bu + Pd(PPh 3 ) 4 NaOH Br (CH 3 CH 2 ) 2 CuLi 6. Write down the major product of the following sequence of reactions. CH 3 1. (CH 3 ) 2 CHCl, AlCl 3 2. HNO 3 , H 2 SO 4 3. KMnO 4 , -OH, heat 4. H +, H 2 O....
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- Spring '09