6_SynapticTransmission

6_SynapticTransmission - Bear: Neuroscience: Exploring the...

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Slide 1 Bear: Neuroscience: Exploring the  Brain 3e Chapter 05: Synaptic  Transmission
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Slide 2 Introduction Synaptic Transmission The process of information transfer at a  synapse Plays role in all the operations of the  nervous system 1897: Charles Sherrington- “synapse” Chemical and electrical synapses 1921- Otto Loewi 1959- Furshpan and Potter, Harvard:  crayfish
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Slide 3 Types of Synapses Direction of Information Flow In one direction: Neuron to target cell First neuron = Presynaptic neuron Target cell = Postsynaptic neuron
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Synapse: The Big Picture http://www.youtube.com/watch?v=D4jCeR1mSe from gyri to information processing. Set to  music. http://www.youtube.com/watch?v=SCasruJT-DU  . Narrated http://www.youtube.com/watch?v=90cj4NX87Yk   Sound effects. h  chemical synapse, vesicles. Narrated. Slide 4 Neuroscience: Exploring the Brain, 3rd Ed, Bear, Connors, and Paradiso Copyright © 2007 Lippincott Williams & Wilkins
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Slide 5 Electrical Synapses Gap junction Channel Connexon- formed by six connexins Cells are said to be “electrically coupled” Flow of ions from cytoplasm to cytoplasm Types of Synapses
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Slide 6 Types of Synapses Electrical Synapses (Cont’d) Very fast transmission Postsynaptic potentials (PSPs) Synaptic integration: Several PSPs  occurring simultaneously to excite a neuron  (i.e. causes AP)
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Slide 7 Types of Synapses Chemical Synapses Most synapses in the human nervous system  are chemical
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Slide 8 CNS Synapses (Examples) Axodendritic: Axon to dendrite Axosomatic: Axon to cell body Axoaxonic: Axon to axon Dendrodendritic: Dendrite to dendrite Types of Synapses
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Slide 9
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6_SynapticTransmission - Bear: Neuroscience: Exploring the...

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