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10Antioxidants

10Antioxidants - I Nutrients Involved in Antioxidant...

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11/26/07 I. Nutrients Involved in Antioxidant Function (Chapter 8) A. Antioxidants – prevent oxidation: when atoms lose an electron) 1. Unpaired electron – free radical (highly unstable) 1. Metabolism – oxidation; free radicals are a natural byproduct 2. Free radicals Also caused by: a. Immune system at work b. Pollution c. Sun d. Radiation e. Tobacco, asbestos 3. Free Radicals damage: a. Cell membrane b. DNA c. LDLs d. Cell protein 4. Diseases linked with free radical production a. Cancer b. Heart Disease c. Arthritis d. Cataracts e. Kidney Disease f. Alzheimers Disease g. Parkinsons Disease 5. Stabilize free radicals by: a. Donating their electrons or H to the free radicals (generally vitamins) b. Stabilize the free radical (beta carotene & phytochemicals) c. Act as a cofactor in our bodies own antioxidant enzyme systems (usually minerals) 6. Protective Antioxidant Systems in Our Body
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a. Catalase – removes hydrogen peroxide from our bodies by converting it to oxygen and water b. Superoxide dismutase – converts free radicals to less damaging substances , such as hydrogen peroxide c. Glutathione peroxidase – removes hydrogen peroxide from our bodies, and stops the production of free radicals in lipids 7.
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