ipsCells

ipsCells - Published online 30 November 2007 | Nature |

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Published online 30 November 2007 | Nature | doi:10.1038/news.2007.219 News A simpler recipe for human stem cells Adult skin cells turned to pluripotent stem cells without a cancer-causing agent. David Cyranoski Cell reprogramming taken one step further.National Institutes of Health Shinya Yamanaka of Kyoto University in Japan has followed the announcement last week of his startling success in turning human skin cells to embryo-like stem cells, by reporting that he has done the same without the cancer-causing agent used in his original recipe. The work brings scientists perhaps one step closer to the goal of being to use patient- matched stem cells for therapy. Yamanaka first demonstrated his method for ‘reprogramming’ cells in mice. Last year he showed that he could produce pluripotent cells — cells that can turn into any of the roughly 220 cell types in the body — by using retroviruses to carry four genes into mouse skin cells 1 . The four genes reprogrammed the mouse cells to a state similar to those in the
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This note was uploaded on 09/14/2009 for the course MCDB 20 taught by Professor Cooper during the Summer '08 term at UCSB.

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ipsCells - Published online 30 November 2007 | Nature |

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