Lecture 19- Retina and photoreceptors

Lecture 19- Retina and photoreceptors - blue cones green...

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rods blue cones green cones red cones
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Green Cones contains opsin most senstive to 531 nm Rods contains rhodopsin most senstive to 496 nm Blue Cones contains opsin most senstive 419 nm Red Cones contains opsin most senstive 559 nm
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light light
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Blind spot- region where photoreceptors are NOT present
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cGMP 5’GMP Ligand that binds to Na+ channels Does NOT bind to Na+ channels Phosphodiesterase
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Light One rhodopsin molecule absorbs one photon 500 transducin molecules are excited 100,000 cyclic GMP molecules are hydrolyzed One million Na ions per second are prevented from entering the cell 500 phosphodiesterase molecules are excited 250 Na channels close +
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Residue 296 is the attachment site for retinal. 11-cis retinal All-trans retinal
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All-trans retinal Active site on opsin is exposed The active site activates transducin and changes rod membrane potential Active site Metabolic energy o o 11-cis retinal rhodopsin ac si Active site Retinal separates from opsin thereby bleaching rhodopsin Metabolic energy brings
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This note was uploaded on 09/14/2009 for the course BIO 365R taught by Professor Draper during the Spring '08 term at University of Texas.

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Lecture 19- Retina and photoreceptors - blue cones green...

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