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Unformatted text preview: activator protein (CAP) to form CAP-cAMP complexes. Such complexes facilitate binding of RNA polymerase to the promoter region, initiating transcription. 21. NH 3 + KG + NADH = H + + Glu + NAD+ Glu + OAA = Asp + KG 22. a. Glu + OAA = Asp + KG b. 23. Fatty acids break down to AcCoA which enters the TCA cycle by condensing with OAA to form citrate. The starting material for gluconeogenesis is OAA. But when citrate is converted to OAA, two carbon atoms are lost as carbon dioxide. So there cannot be a net synthesis of OAA from the Acetyl group of AcCoA, because two carbons enter the cycle and two are lost. In the case of C-odd fatty acids, the three carbon atoms at the methyl end are converted to propionyl CoA, which is converted to methylmalonyl CoA and then to succinyl CoA. The succinyl CoA gives the net synthesis of OAA....
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This note was uploaded on 09/14/2009 for the course MCB 450 taught by Professor Mintel during the Summer '07 term at University of Illinois at Urbana–Champaign.
- Summer '07