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x3fall07-key - activator protein(CAP to form CAP-cAMP...

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Answer Key – Examination 3 – Fall 2007 1. E 2. B 3. B 4. E 5. D 6. D 7. E 8. E 9. B 10. D 11. D 12. E 13. B 14. E 15. E 16. a. an intermediate in the synthesis of ketone bodies (mitochondria) and in the synthesis of cholesterol (cytoplasm) b. vitamin that forms active derivatives that can transfer single carbon atoms at a number of oxidation levels. Important in purine nucleotide biosynthesis c. gives rise to acetoacetate or β -hydroxybutyrate when it is catabolized d. major enzyme of DNA synthesis in E. coli. Has higher V max and processivity than DNA polymerase I. e. Addition of a run of several hundred A-containing nucleotides at the 3 end of eukaryotic mRNA 17. 7 malonyl CoA, 7 ATP, 14 NADPH + H + 18. Non-toxic; highly water-soluble 19. fMet-Ile-Val-Leu-Val 20. Concentration of cAMP varies inversely with that of glucose. When glucose concentrations are high there is very little camp to combine with catabolite
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Unformatted text preview: activator protein (CAP) to form CAP-cAMP complexes. Such complexes facilitate binding of RNA polymerase to the promoter region, initiating transcription. 21. NH 3 + α KG + NADH = H + + Glu + NAD+ Glu + OAA = Asp + α KG 22. a. Glu + OAA = Asp + α KG b. 23. Fatty acids break down to AcCoA which enters the TCA cycle by condensing with OAA to form citrate. The starting material for gluconeogenesis is OAA. But when citrate is converted to OAA, two carbon atoms are lost as carbon dioxide. So there cannot be a net synthesis of OAA from the Acetyl group of AcCoA, because two carbons enter the cycle and two are lost. In the case of C-odd fatty acids, the three carbon atoms at the methyl end are converted to propionyl CoA, which is converted to methylmalonyl CoA and then to succinyl CoA. The succinyl CoA gives the net synthesis of OAA....
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x3fall07-key - activator protein(CAP to form CAP-cAMP...

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