Lecture 11 - Aldhol

Lecture 11 - Aldhol - Before next lab period, complete:...

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Unformatted text preview: Before next lab period, complete: Aldol pre-lab quiz Aldol pre-lab report Nitration post-lab quiz Nitration post-lab report Tutorials Next week is your last experiment. Next lecture: Q/A Session Check-out and Final Exam, the week after break Room locations TBA next time Product: trans- p-anisalacetophenone acetophenone p-anisaldehyde trans- p-anisalacetophenone We form this product via the Aldol Condensation reaction : (1) Formation of -hydroxy carbonyl compound ( Aldol rxn ) (2) Dehydration step to form , -unsaturated carbonyl The Aldol Reaction (Step 1) In this reaction, two molecules of an _________________ combine to produce a -hydroxycarbonyl . A new ____________ is formed between the ___________ of one molecule and the _____________ of the other: aldehyde or ketone New CC bond ALD ehyde alcoh OL C-C bond enol/enolate carbonyl carbon Base-Catalyzed Aldol Reaction Under basic conditions the intermediates bear negative charges Consider how this applies to our reaction...
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Lecture 11 - Aldhol - Before next lab period, complete:...

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