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Unformatted text preview: the ketone starting material UNDER BASIC REACTION CONDITIONS is outlined below. Complete this mechanism by drawing curved arrows to show movement of electron pairs, and by drawing structures for each “missing” reaction intermediate. The final intermediate that forms is a resonance hybrid – please draw only the MOST IMPORTANT contributing resonance structure in the box provided. Ph C CH 3 O NH 2 NH 2 OH H OH OH + OH Δ MORE IMPORTANT RESONANCE STRUCTURE Hydroxide departs as a leaving group - heating is required to overcome the activation barrier (a "strong" base is typically a "poor" leaving group) OH Ph C CH 3 N N H 2 H OH...
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This note was uploaded on 09/14/2009 for the course CH 310n taught by Professor Iverson during the Spring '08 term at University of Texas at Austin.
- Spring '08
- Organic chemistry