Oxidation forms ATP-oxidative phophorylation –atp synthesis w/ reoxidation of e- carriers e- Transport Chain--e-s from NADH and FADH 2 go through membrane e- carriers-drives protons across inner mitochondrial membrane, outta matrix- chemiomsis- protons diffuse through mitochondrial matrix through proton channel, couples diffusion to synthesize ATP-complex to harvest as much nrg as possible- e- transport chain has 4 large protein complexes (1-IV) containing e- carriers and associated enzymes; located on inner mitochondrial membrane; 3 are transport proteins-cytochrome c : peripheral protein on inner mitochondrial space-nonprotein ubiquinone (Q) : is small, nonpolar, and moves freely within hydrophobic region of inner mitochondrial membrane-NAHD + H + transfers es to protein complex (1) NADH + H + NAD + along with transporting protons across inner mitochondrial membrane into the inner membrane space- es transferred to Q- complex (II) passes es to Q also, turns FADH 2 FAD- enter chain after NADH’s e-‘s
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This note was uploaded on 09/15/2009 for the course MOLECULAR 20A taught by Professor Dalbey during the Winter '09 term at UCSC.