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Unformatted text preview: b. If the bonding partner was changed, which two categories would be most likely to disrupt the proteins function? Explain your choices. c. Why could a single change like in part b have an impact on the function of the protein? 3. Many drugs (both legal and otherwise) are functional because they can bind to the same site on a protein as the normal substrate or ligand does. What two general assumptions can we make about a drug of this type as compared to the natural substrate/ligand ? 4. What are the 4 folding-related fates of a newly synthesized protein? If the protein folds quickly, which outcome(s) are least likely? 5. How can chaperonin (hsp60) work with many different and unrelated proteins (i.e. why is it nonspecific in the proteins it can help to fold)?...
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- Fall '09