Lecture 3 - Lecture 3, September 3, 2009 Questions How...

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Lecture 3, September 3, 2009 Questions How close is Bernstein? Bernstein is close in his quantitative prediction, but is he right about the contribution of K? How could we test? Why do you think he might be not quite right? Consequences of leakiness to other ions for equilibrium. Concept of the membrane potential as a steady state Necessity for Na-K pump. Note: we should be able to change this membrane potential by changing the permeability to particular ions. This is exactly what happens when we generate a local potential! An electrical model of the cell membrane (& things this model can teach us) Need it to quantify the electrical behavior of neurons Behavior of resistor, Ohm’s law, V = IR, V = I/g, I = gV ampere = 1 coulomb of charge/sec, coulomb = 6X 10 18 electrons; current flows in neurons will be in nanoamps (nA) volt = work/unit charge = joule/coulomb; voltages in neurons will be in millivolts (mV) ohm = 1 amp in response to 1 volt (reciprocal = siemen); conductances in neurons
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Lecture 3 - Lecture 3, September 3, 2009 Questions How...

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