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1-1 - E-MAIL BioBM3310 QUIZ 1a 1(9 pts Draw the structure...

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E-MAIL BioBM3310 QUIZ 1 a 9/10/08 1. (9 pts) Draw the structure of the dipeptide Cys-Ser at pH 10 . Draw all atoms . Label both α and both β carbons. Show the correct form of each ionizable group. 2. (9 pts) Hemoglobin has a His and an Asp that are close to each other. Estimate the fraction of all these His---Asp neighbors that would be in an ion-pair bond at the following pH values. Circle the best answer from the choices that follow the pH. ______ at pH 8 {1.0} {0} {1/10} {1/100} {9/10} {1/2} {2/3} ______ at pH 6 {1.0} {0} {1/10} {1/100} {9/10} {1/2} {2/3} ______ at pH 7 {1.0} {0} {1/10} {1/100} {9/10} {1/2} {2/3} 3. (7 pts) PyMOL questions about the image on the right (also projected on the screen): a. Circle the one menu choice below that gave the image shown. [lines sticks ribbons cartoons spheres branches rods] b. Directly on the image, circle BOTH peptide bonds c. Write the name of this peptide. Use 3-letter abbreviations. _______________________________ 4. (5 pts) Glycine, lysine, and glutamate are each free amino acids. Gly-Lys-Glu is a tripeptide. Write in the correct answers below: a. Compared to the free AA, how many + charges are lost when the tripeptide forms? ___ b. Compared to the free AA, how many - charges are lost when the tripeptide forms? ___
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