Lecture 2 - Box 7-1 Imagine two compartments with equal...

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Unformatted text preview: Box 7-1 Imagine two compartments with equal concentrations of ions separated by a permeable membrane. 100 K + 100 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- Is there a potential difference (i.e.--voltage) across the two compartments? 100 K + 100 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- Is there a potential difference (i.e.--voltage) across the two compartments? NO! 100 K + 100 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- Each compartment is electroneutral (same # of positive and negative charges). There is no net difference in charge between the two compartments. Note: What is voltage? Voltage is the separation of charge between two points. The greater the difference in charge, the greater the voltage. It is a relative measurement. Do ions move freely from one compartment to the other? 100 K + 100 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- Do ions move freely from one compartment to the other? YES! 100 K + 100 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- Ions move by random (Brownian) motion. Is there a net movement of either ion from one side to the other? 100 K + 100 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- Is there a net movement of either ion from one side to the other? NO! 100 K + 100 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- Now imagine two compartments separated by a permeable membrane but with different concentrations of ions in each compartment (ignoring osmolarity). 200 K + 200 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- K + K + K + K + Cl- Cl- Cl- Cl- Is each compartment electroneutral? Is there a voltage across the two compartments? 200 K + 200 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- K + K + K + K + Cl- Cl- Cl- Cl- Is each compartment electroneutral? YES! Is there a voltage across the two compartments? NO! 200 K + 200 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- K + K + K + K + Cl- Cl- Cl- Cl- Is there a net movement of ions from one side to the other? 200 K + 200 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- K + K + K + K + Cl- Cl- Cl- Cl- Is there a net movement of ions from one side to the other? YES! 200 K + 200 Cl- 100 K + 100 Cl- K + K + K + K + K + K + K + K + Cl- Cl- Cl- Cl- Cl- Cl- Cl- Cl- K + K + K + K + Cl- Cl- Cl- Cl- Both K + and Cl- move down their concentration gradients, from the left compartment into the right compartment. What will the final concentrations be in each compartment?...
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Lecture 2 - Box 7-1 Imagine two compartments with equal...

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