Discussion 3 - CELL BIOLOGY (BIO 320) FALL 2009 Discussion...

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CELL BIOLOGY (BIO 320) FALL 2009 Discussion 3 _______________________________________________________________ 1. Panels of human-rodent cell hybrids that retain one or a few human chromosomes, parts of human chromosomes, or radiation-induced fragments of human chromosomes have proven enormously useful in mapping genes to defined locations. You wish to map the location of the receptor for feline leukemia virus type C (FeLV-C), which will infect human cells but not rodent cells. Using a panel of hybrid cells carrying whole chromosomes, you have shown that FeLV-C infects only those hybrids carrying human chromosome 1. Using a second panel carrying portions of chromosome 1, you show that FeLV-C infects several of the hybrid cell lines. The segments of chromosome 1 that are present in the infectable hybrid cell lines are shown in the following figure. Portions of human chromosome 1 retained in the individual cell lines are indicated as vertical lines. Where on chromosome 1 is the gene for the FeLV-C receptor located? 2.
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This note was uploaded on 09/22/2009 for the course BIO 320 taught by Professor Staff during the Fall '08 term at University of Texas at Austin.

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Discussion 3 - CELL BIOLOGY (BIO 320) FALL 2009 Discussion...

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