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Lecture 12, Ch. 26 - radiation enhances complex molecule...

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Lecture #12 Date _______ Chapter 26 ~ Early Earth and The Origin of Life
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Early history of life Solar system~ 12 billion years ago (bya) Earth~ 4.5 bya Life~ 3.5 to 4.0 bya Prokaryotes~ 3.5 to 2.0 bya stromatolites Oxygen accumulation~ 2.7 bya photosynthetic cyanobacteria Eukaryotic life~ 2.1 bya Muticelluar eukaryotes~ 1.2 bya Animal diversity~ 543 mya Land colonization~ 500 mya
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The Origin of Life Spontaneous generation vs. biogenesis (Pasteur) The 4-stage Origin of life Hypothesis: 1- Abiotic synthesis of organic monomers 2- Polymer formation 3- Origin of Self- replicating molecules 4- Molecule packaging (“protobionts”)
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Organic monomers/polymer synthesis Oparin (Rus.)/Haldane (G.B.) hypothesis (primitive earth): volcanic vapors (reducing atmosphere) with lightning & UV
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Unformatted text preview: radiation enhances complex molecule formation (no O2) ● Miller/Urey experiment: ● water, hydrogen, methane, ammonia ● all 20 amino acids, nitrogen bases, & ATP formed ● Fox proteinoid formation (abiotic polypeptides) from organic monomers dripped on hot sand, clay or rock ● Oparin (coacervates) protobionts (aggregate macromolecules; abiotic) surrounded by a shell of H2O molecules coated by a protein membrane Abiotic genetic replication ● First genetic material ● Abiotic production of ribonucleotides ● Ribozymes (RNA catalysts) ● RNA “cooperation” ● Formation of short polypeptides (replication enzyme?) ● RNA~ DNA template? The Major Lineages of Life Classification QuickTime and a Cinepak decompressor are needed to see this picture....
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