Immune074 - 10 Specific Defenses Cell-mediated (T) Humoral...

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1 Components of the Lymphatic and immune System Rt.lymph.Duct Thoracic duct Drain interstitial fluid Transport lipids* & lipid soluble vitamins Immune function Primary (RBM, thymus) Secondary (nodes, spleen, nodules)
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2 Lymphatic Capillaries Note: one-way flow…
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3 Note: order of flow blood--> interstitial --> lymph --> blood
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4 Structure of a Lymph Node
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5 -Associated Lymphoid Tissues Nodules Lymph tissue without capsule Passageways MALT GALT
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6 Non-specific Immune Responses First line: Skin, mucuous membranes Why? Second line: Interferon, transferrin, complement (30) Natural Killer Cells Neutrophils, Macrophages Inflammatory Response Complement proteins are activated via 3 pathways: w/ or w/o Ab or lectin
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7 QuickTime™ and a MPEG-4 Video decompressor are needed to see this picture. Macrophage and bacillus
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8 Inflammation
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9 Summary of Nonspecific Resistance What happens during viral infection? 1st line… 2nd line… 3rd line… What would happen to any pathogens Holly swallowed?
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Unformatted text preview: 10 Specific Defenses Cell-mediated (T) Humoral (B) 11 Specific Immunity Ag-Ab MHC APC 12 Antigen Presenting Cell 13 14 Classes of Immunoglobulins 80% Secretions First responder Allergy B-cell activation Self-tolerance 15 APCs: Macrophages, B-cells, dendritic cells MHC: Major Histocompatibility Complex 16 T-cell Activation: APC + Helper T + Interleukin 1 --> IL2 release --> Helper T, Cytotoxic T and B-cell activation --> More cells, Cellular response (cytotoxic), Humoral response (plasma cells and antibodies) MHC 17 Immunity 18 Secretion of Antibodies Immunity 19 Types of Immunity 20 Summary Lymphatic system: fluid, circulation, structures Non-specific Immune Responses: 1st and 2nd Lines of Defense Specific Immune Response: 3rd Line: Cellular and Humoral Responses Antigen-antibody complexes Immunity Disease: Stages of a viral infection...
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Immune074 - 10 Specific Defenses Cell-mediated (T) Humoral...

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