Musclept2N2087

Musclept2N2087 - Muscles 2: Contraction & Relaxation of...

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1 Muscles 2: Contraction & Relaxation of Skeletal Muscle Metabolism in Skeletal Muscle Control of Muscle Tension & Tone Types of Skeletal Muscle Cells
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2 Contraction/Relaxation Excitation-Contraction Coupling Contraction Cycle: Attachment Pivoting Detachment Return
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3 Power Stroke Myosin ATPase splits ATP into ADP + P Myosin heads attach to actin P release causes head to swing like an oar Powerstroke ADP released, myosin bound to actin (rigor) ATP binding to myosin releases actin
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4 Relaxation Contraction cycle continues UNTIL: Ca++ levels return to normal OR Cell runs out of ATP
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5 Energy sources in muscle cells Creatine phosphate Lactic acid fermentation Aerobic
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6 Metabolism Rapid changes from very low ATP consumption to high levels of consumption Creatine phosphate (high energy store) ~ 15 -30 sec
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7 Glycolysis Break down glucose to 2 pyruvates getting 2 ATPs If insufficient mitochondria or oxygen pyruvate => lactic acid Get about 30-40 seconds more at max.
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8 Aerobic Cellular Respiration Production of ATP in mitochondria Requires oxygen and carbon substrate • Produces CO 2 and H 2 O and heat.
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Musclept2N2087 - Muscles 2: Contraction & Relaxation of...

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