genetics exam 3 martens

Genetics exam 3 - BIOSC 0350 Spring Term 2084 Third Mid-Term Exam Dr Joe Martens Name Signature Answer key Print INSTRUCTIONS 1 Print your name at

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BIOSC 0350 Name: Spring Term 2084 Third Mid-Term Exam Signature: April 10, 2008 Dr. Joe Martens INSTRUCTIONS: 1. Print your name at the top of each page and make sure you have 13 exam pages that includes one page of scrap paper. 2. Sign the first page of this examination in the space provided. 3. Take a few moments to look over the entire exam before answering any questions. Then, begin with the questions you are most comfortable answering. 4. Show your work. In some cases partial credit will be given. 5. Please write legibly. Make your drawings clear. Be concise; you will not be given credit for extraneous information. 6. Some of the model systems described in this exam parallel actual genetic systems but are solely derived from the imagination of the instructors. 7. Remember to relax and do your best. Good Luck!! Be sure to attempt all of the questions. If you are having difficulty with any one question or one part of one question, move on and come back to these later. Print Answer key
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Name Page 2 of 13 BIOSC 0350 Mid-Term Exam 1 April 10, 2008 Question Possible Points Score 1 20 2 12 3 20 4 18 5 16 6 14 Total 100
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Name Page 3 of 13 BIOSC 0350 Mid-Term Exam 1 April 10, 2008 1. 20 points (2 points/question) Answer the following multiple-choice questions by circling the correct answer. i) The house mouse, Mus musculus , has a diploid chromosome number of 40. A disomic gamete would have how many chromosomes? A. 41 B. 40 C. 20 D. 21 E. 80 ii) Which of the following do translocations and inversions not have in common? A. don't alter the amount of DNA in the genome B. ability to alter gene function C. use of inversion loops during crossing over D. a phenotype is often dependent on position of double strand break iii) When detecting SNPs, the lack of strong hybridization by an allele specific probe of about 20 bases to DNA to be tested detects A. a normal, unchanged sequence. B. a polymorphic sequence. C. the probe is too short. D. the probe is too long. E. inappropriate protocol. iv) The components of a chromosome include one long DNA molecule and A. phospholipids. B. proteins. C. carbohydrates. D. steroids. E. RNA. v) Which of the following statements is false regarding X-inactivation? A. Compaction of X chromsome spreads from Xic (X-inactivation center) B. Xist RNA coats the X chromosome to be inactivated C. Most genes on inactivated X chromsome are silenced D. Xist encodes a protein required for X inactivation E. Random X-inactivation generates mosaics
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Name Page 4 of 13 BIOSC 0350 Mid-Term Exam 1 April 10, 2008 vi) In general, which of the following usually has a greater chance of lethality than the others? A. inversion B. duplication C. deletion D. translocation E. All have an equal chance. vii) A strain of
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This note was uploaded on 09/25/2009 for the course BIOSC 350 taught by Professor Martens during the Spring '07 term at Pittsburgh.

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Genetics exam 3 - BIOSC 0350 Spring Term 2084 Third Mid-Term Exam Dr Joe Martens Name Signature Answer key Print INSTRUCTIONS 1 Print your name at

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