Lecture 17 Guide

Lecture 17 Guide - Cancer
as
a
Genetic
Disease


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Unformatted text preview: Cancer
as
a
Genetic
Disease
 I.
Cancer
arises
at
the
level
of
an
individual
cell
 
 

 II.
Balance
between
cell
division
and
cell
death
 III.
Multi‐hit
process
 
 A.
Tumor
suppressors
 
 B.
Oncogenes
 IV.
Prevention
and
treatment
 

































Cancer
as
a
Genetic
Disease
 Objectives:
 Know
how
each
of
the
vocabulary
terms
fits
into
a
discussion
of
cancer
 Answer
why
cancer
is
often
termed
a
disease
of
old
age
 Vocabulary tumor suppressor oncogene predisposition somatic mutation mutation accumulation cell cycle apoptosis checkpoints p53 growth factors and receptors retinoblastoma xeroderma pigmentosum signal transducers DNA repair Normal cells and cells transformed by an oncogene The ras oncogene is continuously active Table
12‐2
 Cancer by somatic translocation Figure
16‐35
 The Ames test reveals mutagenic compounds Figure
15‐20
 Assignment

 Achieve
Objectives
List
(slide
2)
through
study
 and
practice.
 Solve
problems
from
textbook.

 Chapter
15:

 33
 ...
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This note was uploaded on 09/26/2009 for the course BIS 98659 taught by Professor Kimbrell during the Summer '09 term at UC Davis.

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