BIOL 200 - Lecture PNS

BIOL 200 - Lecture PNS - DrugsofthePeripheralNervousSystem

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Drugs of the Peripheral Nervous System
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Nervous System’s 2 Divisions y Central y Brain y Spinal Cord y Peripheral y Voluntary y Involuntary Autonomic y Sympathetic y Parasympathetic
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Effector Cells of the Peripheral Nervous System y Voluntary y Skeletal Muscle y Autonomic y Cardiac Muscle y Smooth Muscle y Glands
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The Autonomic Nervous System y The ANS is an efferent system that governs functions without conscious effort. y The signals are outward bound originating from the CNS and traveling to the periphery. y Most smooth muscle, cardiac muscle, exocrine glands, airway secretions are under the control of the ANS.
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How many efferent neurons do we find in the voluntary nervous system ? O n e Two Three 81% 3% 17% 1. One 2. Two 3. Three
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Branches of the ANS y 2 distinct branches y Sympathetic Nervous System (SNS) y Parasympathetic Nervous System (PNS)
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SNS y Fight orflight y Increase heart rate y Blood volume shifts to skeletal muscles y bronchodilation
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PNS y Restorative functions: “rest and digest” y Increase gastrointestinal motility y Increase visceral blood flow y Decrease heart rate
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Anatomical Differences y 2 neuron system y Pairs of neurons linked together y Action potentials driven through sodium channels across synapses y Chemical communication at ganglia and junction with target organ
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Ganglia y In the ANS synapses occur at ganglia y Ganglia = bundles of synapses y Neurons of the ANS travel in groups and make connections in the ganglia y Anatomically, ganglia look like a bulge
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Neurons of the ANS y Preganglionic y Postganglionic
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Sympathetic Nervous System y Fibers leave the CNS in the thoracic and lumbar regions of the spinal cord y The ganglia are located around the spinal column y The targets are located all over the body. y The adrenal gland is like an overgrown sympathetic ganglion with targets all over the body via the blood
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Sympathetic Neurons Preganglionic neurons located in the thoracic and lumbar region Synapse in 2 cord-like chains of ganglia that run parallel on each side of the spinal cord Long postganglionic neurons
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The Parasympathetic Nervous System y Fibers leave the CNS in the cranial and sacral regions. y Ganglia are right on the target organ (long pre ganglionic fibers) y The targets are restricted to visceral organs y Kidney, GI tract, eye, heart…not skin, extremities…restricted to internal organs
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Parasympathetic Preganglionic neurons arise from cranial/sacral regions of spinal cord & synapse in ganglia near or on the effector organ (short postganglionics)
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of the chemicals that they use y Neurotransmitters: mediate signals between cells/targets y Neurotransmitters received by down stream cell and produce a response. y
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This note was uploaded on 09/26/2009 for the course BIOL 200 taught by Professor Egan during the Summer '09 term at Golden West College.

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BIOL 200 - Lecture PNS - DrugsofthePeripheralNervousSystem

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