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BMED213Lecture_2 - ENGR213/BRAE213 Biology for...

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    ENGR213/BRAE213 Biology for Engineers “The Central Dogma of  Molecular Biology”
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    Some Background Information • Central Dogma of Molecular Biology ---  Transfer of information from Genetic Code  to Proteins (Proteins : the building blocks of  life) • Goals for today: – Give you the picture of flow of “Genetic”  information – Cover the key Biological Constituents involved  in the flow of Genetic information
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    The Flow of Information • Reception of Cellular Signal • Signal Transduction • Gene transcription factors (enter nucleus) • Transcription of Genetic Code – DNA to mRNA • mRNA Transport out of the nucleus • Ribosomal Translation from mRNA to amino- acids to protein • Protein - a collection of amino-acids that have a  particular function; the building blocks of life
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    The Central Dogma of Molecular  Biology Molecular Machine (a collection of proteins that  perform a particular function) The flow of information: • Genetic Code (Exons) DNA • Transcription into mRNA  (messenger RNA) • Translation of mRNA into  Protein and Molecular machines The Flow of Information Where does this all occur ? What is involved ?
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    Some Basic Anatomy of a  Eukaryotic Cell Cell Membrane Cytoskeleton Mitochondria Maternal DNA Production of ATP 
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