09.21 - Ion Channels operate in many ways Leak channels...

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Leak channels Gated channels- voltage ligand (chemical) pressure (mechanical) stretch light (electromagnetic) temperature Ion Channels operate in many ways: Acetylcholine (+) Glutamate (+) GABA (-) Glycine (-) Dopamine Norepinephrine/epinephrine Serotonin Histamine Peptides/ATP Endocannabinoids Endorphins Synapses Chemical: Acetylcholine (Ach)
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ACh receptors: NMJ - 90 mV - 50 mV - 10 mV +50 mV Reversal potential ACh receptors: composed of subunits
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Ionotropic Metabotropic Nicotinic Muscarinic Acetylcholine Receptors ACh Receptors Acetylcholine
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mACh Receptors Agonist vs Antagonist agonist | ˈ ag ə nist| | ˌ øg ə n ə st| | ˌ ag ə n ɪ st| Biochemistry a substance that initiates a physiological response when combined with a receptor. Often contrasted with antagonist . antagonist Biochemistry a substance that interferes with or inhibits the physiological action of another. Compare with agonist .
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