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F08pages43-55

F08pages43-55 - Summary DNA is a double-stranded helix...

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Summary • DNA is a double-stranded helix, sugar-phosphate backbone on the outside, base pairs (A=T, G=C) on the inside, strands anti-parallel. • DNA polymerase III cannot initiate synthesis, and only synthesizes in the 5’to 3’ direction. One DNA strand is synthesized continuously, the other discontinuously. • Primase makes a short RNA primer which provides DNA polymerase III with a 3’-OH for DNA synthesis. • DNA polymerase I removes the RNA primer and replaces it with DNA. • Ligase makes the Fnal phosphodiester linkage. Questions for Chapter 16 7th Edition 8th Edition • Concept Checks – 16.1 (questions 3-4). – 16.2 (questions 1-4). • Self-Quiz Questions 2-6, 8-9. • Concept Checks – 16.1 (questions 1-2). – 16.2 (questions 1-3). • ±igure 16.4, 16.11, 16.12, 16.14 questions. • Self-Quiz Questions 2-7. Chapter 17 ±rom Gene to Protein • DNA -> RNA -> Protein • Gene transcription by RNA polymerases. • RNA translation by ribosomes. The genetic code. • Gene structure - promoters, introns, exons. • RNA structure - polyA tails, caps, splicing. • Molecular basis for mutations. Reading assignment - all of Chapter 17 in 7th or 8th edition. Ribosome and tRNAs 43
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How is genetic information used in cells?
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F08pages43-55 - Summary DNA is a double-stranded helix...

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