5_8_07 - May 8, 2007 Biology 130 Immune System Immune...

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May 8, 2007 Biology 130 Immune System Immune system o Protects from pathogens Pathogen o Anything that causes an immune response Viruses Bacteria Protista Malaria Animals Nematodes “worms” Toxins (elements) Heavy metals o Not allergies Mechanisms to fight Pathogens o All non-specific, fight pathogens indiscriminately by recognizing glycoproteins o Mechanical barriers Skin Mucus membranes Secretions o Chemical barriers Acidic environments Stomach Vagina Secretions Sweat Salts Sebum “gil” Urea Fatty acids Enzyme o Defensin (skin) o Lysozyme (tears) o Biological barriers Microorganisms On skin In GI tract Non specific mechanisms
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o Recognizes groups of glycoproteins o Glycoproteins (cell-cell indentificaiton) Toll-like receptor Binds nonspecifically Specific mechanisms o Antigens recognized by antibodies or T-cell receptors White Blood Cells o Neutrophil Non specific
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5_8_07 - May 8, 2007 Biology 130 Immune System Immune...

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