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3_29_07 - Biology 130 Molecular Genetics 1 DNA replication...

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March 29, 2007 Biology 130 Molecular Genetics 1. DNA replication 2. Central Dogma 3. Protein synthesis a. Transcription b. Translation 4. Gene Control 5. Recombinant DNA – lab mainly Two classic examples to discover if DNA is genetic material. DNA vs protein as genetic material. DNA wasn’t diverse enough to be genetic material o Griffith and Avery. Bacteria into mice. Some ingredient that transfers from virulent strain to non-virulent strain to kill mice o Hershey-Chase. Bacteriaophage injects something into the bacterial cell to create phage (viruses). Tagged sulfur in protein and phosphorus in DNA. Discovered tagged information in the bacteria cells. o Laid the foundation that DNA is genetic information Monomers of the polymer DNA are nucleotides o Thymine, adenine, cytosine, guanine o Runs 5' to 3' complimentary strand has 5' at bottom and 3' at top o Adenine and guanine are purines o Thimine and cytosine are pyrimidines o DNA doesn’t shift in width therefore the must be purine with pyrimidine o
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