3_8_07 - March 8 2007 Biology 130 Cellular Aerobic...

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March 8, 2007 Biology 130 Cellular Aerobic Respiration Main objective – create ATP Energy stored into organic molecules need to be converted Use ATP to o Transport molecules across membranes – concentration gradients o Muscle contractions o ATP – GTP for signal transduction – role of ATP in biology o Synthesis of materials – phosphorylate molecules General formula C 6 H 12 O 6 + O 2 6CO 2 + 6H 2 O delta G = -686 kcal/mol ADP – P 2 ATP 3 Parts Glycolysis Krebs cycle – citric acid cycle Oxidative phosphorylation (uses e - chain) Glycolysis C 6 H 12 O 6 broken down into 2 moles of pyruvate to generate some ATP Happens in cytoplasm Do not need mitochondria White muscle fibers and red blood cells only do glycolysis. White muscle fibers don’t need O 2 so there is little blood supply Why do we even have white muscle fibers? Can work faster but only over a short period of time – weightlifters and sprinters. Long distance athletes have red muscle fibers. Has to do with genetics. Not much we can do about the amount of red v. white muscle fibers Most energy is left in the pyruvate Citric Acid Cycle In the matrix of the mitochondria Break down 2 pyruvate into 6 carbon dioxide (completely) Generate some ATP
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