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Chap 6, life course plot - 136 HUMAN DEVELOPMENI UFE COURSE...

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Unformatted text preview: 136 HUMAN DEVELOPMENI. UFE COURSE. INTERVENTION AND HEALTH 48. Karoly LA. Kilburn MR, Cannon )5, Bigelow 1H. Christina R (2005). Many happy returns: early childhood programs entail costs. but the paybacks could be substantial. Rand Review 29, 10-17. 49. Elder GH (1986). Military times and turning paints in men's lives. Developmental Psychology 22. 233-24 5. 50. Werner EB (1989). High-risk children in young adulthood: a longitudinal study from birth to 32 years. American Iaurnnl ofOrthoprychiurry 59. 72—81. 51. lrwin LG. Siddiqi A. Hertzman C (2007). Early child development: a powerful equalizer. Final Report for the World Health Organiution’s Commission on the Social Determinants of Health. Human Early Learning Partnership. WHO. Geneva. 52. Belsky l. Melhuish E. Barnes l. Leyland AH. Romaniuk H (2006). Effects ofSurc Start local programmes on children and families: early findings from a quasi-experimental. cross sectioml study. British Medical Journal 332. 1476—1481. 53. Janus M. Offord DR (2000). Reporting on readiness to learn in Canada ISUMA. Canadian laurnal of Policy Research 1. 71-75. 54. D'Anguilli A, Warburton W. Lloyd IEV. Kinar K. lrwin L. Dahinten S. llertzmrtn C (submitted). Grade-four basic skills are associated with pre-school vulnerability. 55. Ostry A. Marion SA. Green I... Dcmers PA. Hershler R. Kelly S. et al. (2000). Downsizing and industrial restructuring in relation to changes in psychosocial conditions of work in British Columbia sawmills. Scandinavian Iournal of Work. Environment and Health 26. 273—278. 56. Chamberlaync 8. Green B. Bauer ML. Hertzman C. Lawrence W]. Shep: 58 (I998). Creating a populationbascd linked health database: a new resource for health services research. Canadian Journal of Public Health 89. 270—273. 57. Ostry A. Tanscy i. Maggi S. Dunn l. Hershlcr R. Chen L. et al. (2006). The impact of father's physical and psychosocial work conditions on attempted and completed suicide among their children. BMC Public Health 6. 77. 58. Rutter M. Pickles A.. Murray R. Eaves l. (2001 ). Testing hypotheses on specific environmental causal effects on behaviour. Psychological Bulletin 127, 291—324. Chapter 6 The life course plot in life course analysis Tim Cole Abstract This chapter considers the life course in the context of an outcome in later life as related to early growth status, where each subject is assumed to have been measured as a child at two or more pro-specified ages. The analysis is by multiple regression. with the outcome as the dependent variable and the measurements at each age (expressed as z-scores) as the independent variables. This analysis highlights measurements at any particular age(s) that are predictive of outcome (size effects), and simultaneously flags the predictive value of changes in the measurement over different time intervals (i.e. growth effects). Size and growth are intimately related. and the life course plot helps to interpret the results. 6.1 Introduction 6.1.1 Life course Life course research involves the health and lifespan of individuals. and it arises in many areas of research including psychology, sociology. demography, anthropology and biolo- gy.l It relates an outcome later in life, commonly health—related, to factors operating at different stages earlier in life. In the context of chronic disease epidemiology. the life course approach has been defined as the study of long-term effects on chronic disease risk of physical and social exposures during 36- tation. childhood. adolescence. young adulthood and later adult life. It includes studies of the bio- logical. behavioural and psychological pathways that operate across an individual's life course. as well .15 across generations, to influence the development of chronic diseases.2 One characteristic of life course chronic disease epidemiology is that while the out- come is health based. the earlier exposures are often social or behavioural. representing suy inequality measured by socio-cconomic status or lifestyle. In contrast to this, one area of chronic disease epidemiology that has come to the fore in the past two decades has an explicitly biological early exposure. the size and growth of the individual in early life. 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