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Lecture 4_RiskAssessmnt_Sept 8

Lecture 4_RiskAssessmnt_Sept 8 - Assessing Human Risk Why...

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Assessing Human Risk Why do we need risk assessment? What is risk assessment? È How does it differ from other hazard management strategies? È The major components of a risk assessment Risk assessment example Risk assessment and risk management
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Why do we need risk assessments? Number of new chemicals >> chemical impact research 24 million chemicals in the Chemical Abstracts Services (CAS) Registry (4,000 added per day) 70,000 chemicals formulations in commerce (1000 added/year) 3 300 high production volume (HPV) chemicals [more than 1 million AND 3,300 high production volume (HPV) chemicals [more than 1 million pounds/y produced] 900 Substances reviewed by the International Agency for Research on Cancer 500 Chemicals in the EPA Integrated Risk Information System database 95 known human carcinogens 133 000 chemicals in the Registry of Toxic Effects of Chemical 133,000 chemicals in the Registry of Toxic Effects of Chemical Substances (RTECS) database (mainly with only LD50 studies)
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