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2 - Lecture 2 Intracellular processing and transport of ECM...

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1 Intracellular processing and transport of ECM molecules Molecular Organization of collagens Collagen Classification Fibrillar collagens: structure and assembly of type I collagen (prototype) Intracellular Processing September 10, 2008 Lecture 2
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2 Overview of Intracellular Protein Traffic nucleus Secretory Pathway for ECM molecules mRNA Translation arrest Endoplasmic reticulum Golgi NH 2 COOH Secretory vesicles Figure 12-6. Molecular Biology of the Cell, 4 th edition Plasma membrane
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3 http://www.molecularexpressions.com/cells/animals/images/animalcellsfigure1.jpg Anatomy of a cell How does a cell decide which proteins are destined to be translated in the cytoplasm or in the endoplasmic reticulum?
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