Principles of Drug Action (BIO 365D) Test #3 Name:_____________________________April 27, 2009Each of the 12 multiple choice questions is worth 0.75 marks out of 30.1.Which of the following statements regarding teratogenicity is FALSE? A.Alkylating agents (such as cyclophosphamide) that are used to treat cancer are also teratogenic.B.Teratogens can act in a highly specific manner, with some having effects on some points in development whileothers exert their effects at different times .C.Lipophilic teratogens are expected to exert their teratogenic effects for only a brief period following exposure.D.Animal studies can fail to detect teratogenicity due to differences in inter-species sensitivity to teratogens.E.Hydrophilic teratogens are expected to exert their teratogenic effects for only a brief period following exposure.2.The time period LEASTsensitive to teratogens isA.Fetal periodB.Embryonic period.C.The time between fertilization and implantation of blastocyst.D.The time during development doesn’t matter - all times exhibit equal degrees of susceptibility.E.The postnatal period. 3.Which one of these behavioural tests is NOTa test of an instinctive behaviour?4.Which of the following drugs impairs formation of new memories, leading to amnesia?5.Which one of the following projections between brain regions is strongly implicated in mediating the reinforcingeffects of drugs of abuse? 6.Which of the following drugs produces its pharmacological effects promoting dopamine release? A.EcstasyB.MethamphetamineC.CocaineD.LSDE.Marijuana
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