Lecture seven 10 10 08

Lecture seven 10 10 08 - Comparison of silibinin alone to...

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Retrospective study Comparison of silibinin alone to silibinin + penicillin Amatoxin poisonings treated between 1957 - 2005 Silibinin alone Silibinin + Penicillin 130 258 1 death = 0.8% 21 deaths = 8%
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Retrospective study Subjects may not be well matched Low cost No ethical problems in establishing control groups Advantages Feasibility
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Always cook mushrooms Inactivate toxins
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Inactivate toxins Morels Button mushrooms
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Always cook mushrooms Kill bacteria eliminate risk of bacterial food poisoning
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Eat a small quantity the first time
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¾ Does not turn a silver vessel black ¾ It can be peeled ¾ Doesn’t kill a chicken ¾ A squirrel ate one No simple tests to determine if a mushroom is poisonous
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Fungi in mythology and religion People incorporate the natural world into their mythologies Plants and animals
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Gordon and Valentina Wasson Very strong reactions to fungi
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Mushrooms played a role in many religions Most are dead or practiced secretly actively suppressed
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Mushrooms played a role in religion Most are dead or practiced secretly actively suppressed Or maybe not
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Interest in spiritual uses of mushrooms derives from their potentially mind- altering properties
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AMANITA MUSCARIA Fly agaric
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AMANITA MUSCARIA Mario mushroom
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Found in Northern Hemisphere forests Worldwide
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North America Asia Europe Found in Northern Hemisphere forests Worldwide
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Pines Mycorrhizal Introduced to Southern Hemisphere Transported with seedlings
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Flies are attracted to the mushroom Feed on surface Fly agaric
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This note was uploaded on 10/03/2009 for the course SAS 30 taught by Professor Wilhelm during the Fall '08 term at UC Davis.

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Lecture seven 10 10 08 - Comparison of silibinin alone to...

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