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Normal Liver Function and Abnormalities Associated with Disease Anatomy Normal Liver Function Abnormalities Caused by Liver Disease Bile salts Emulsify fats to aid in absorption Steatorrhea Vitamin K deficiency Bilirubin Waste product of hemoglobin breakdown Jaundice Common Bile Duct Drain bile from hepatic and cystic ducts into duodenum Fatty acid and vitamin A, D, E and K malabsorption Metabolic bone disease Cystic Duct Drain bile from gallbladder Decreased flow of bile Cholestasis Hyperlipidemia Hypercholesterolemia Hepatic Duct Drain bile from hepatocytes into cystic duct Decreased flow of bile Cholestasis Hyperlipidemia Hypercholesterolemia Steatorrhea Hepatocytes Metabolize nutrients Produce bile Store vitamins Synthesize plasma proteins Impaired carbohydrate, protein and fat metabolism Coagulopathy Decreased clotting factors
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Unformatted text preview: Fatty liver Hepatic encephalopathy Vitamin deficiency Decreased insulin production Kupffer Cells Remove bacteria from blood Jaundice Increased risk of infection Portal System Directs blood flow to and from the liver Impaired blood flow Portal hypertension Decreased transport of nutrients Hepatic Artery Supplies oxygenated blood to the liver Decreased oxygenation Cell death Hepatic Portal Vein Carries nutrient-rich blood from digestive organs to the liver Portal hypertension Esophageal varices Gastric bleeding Ascites Hepatic Vein Drains deoxygenated blood from the liver; ultimately drains into the inferior vena cava Impaired blood flow Sinusoids Location where nutrients flow from blood into hepatocyte Cell damage Impaired nutrient metabolism Source: Ariyan: Nutrition Management of Liver Disease (Support Line, 12/04)...
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This note was uploaded on 10/04/2009 for the course NTR 371 taught by Professor Southworth during the Spring '09 term at University of Texas.

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