POTENTIALLY HEPATOTOXIC HERBAL SUPPLEMENTS Herb Comments Borage Suggested as a tonic for the adrenal glands reducing stress; may be used as a source gamma linolenic acid (cheaper than primrose oil) ± May contain hepatotoxic and carcinogenic pyrrolizidine alkaloids Chaparral (creosote bush) Once thought to have medicinal properties for treatment of arthritis, cancer, menstrual cramps, etc. ± Documentation of at least 6 cases of hepatitis. At least one individual required a liver transplantation Coltsfoot Once used to treat coughs and sore throats ± Contains a hepatotoxic pyrrolizidine alkaloid called senkirkine, which is also a carcinogen DHEA (dehydro-epiandrosterone) A hormone made by adrenal glands and liver that serves as a precursor to steroid hormones (testosterone, estrogen, adrenalin). Once marked for variety of uses such as weight loss. ± Can cause hepatic dysfunction Echinacea Enhances the immune system by stimulating phagocytosis, increasing respiratory activity and increasing the mobility of leukocytes
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This note was uploaded on 10/04/2009 for the course NTR 371 taught by Professor Southworth during the Spring '09 term at University of Texas.