Lect8 - 15-20 Differences in peptide binding between MHC...

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Fig. 5-23 Lehn
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Fig. 15-12 B and T Four beta strands from each of the variable domains (V H and V L ) each form half of a beta barrel
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B and T 15-13 Space-flling model oF the hypervariable regions oF an ±ab Fragment
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Complex between lysozyme (antigen - in green ) and antibody ( blue and yellow ) Regions of contact are red . B and T 15-15
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Environment of Gln 121 (purple in previous slide) in the lysozyme- antilysozyme complex B and T 15-16
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Fig. 5-27 Lehn
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Fig. 5-27 Lehn
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Fig. 5-27 Lehn
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Fig. 5-27 Lehn
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Fig. 15-18 B and T MHC complex protein structure
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Fig. 5-22 Lehn
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Fig. 15-19 B and T Peptide-binding groove of a class I MHC protein (viewed from the top)
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B and T
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Unformatted text preview: 15-20 Differences in peptide binding between MHC class I and II B and T 15-21 T-cell receptors, like Ig molecules, have variable and constant Ig domains B and T 15-22 Note the similarities in structure between Ig molecules and T-cell receptors B and T 15-23 Side view of T-cell receptor (top), bound to class I MHC (bottom) with bound peptide Bound peptide in yellow Antibodies can be used to probe for proteins that are only a small percentage of a complex mixture (immunoblotting) Antibodies can be used to visualize specific types of cells in a tissue...
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Lect8 - 15-20 Differences in peptide binding between MHC...

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