Lect5 - Protein Kinase Domain Alignments (all of the N...

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Protein Kinase Domain Alignments (all of the N lobe, part of the C lobe) < 1> P loop <-- 2--> <-- 3--><- B-> A002101_Rsk3 43 ISNHVKEGFE K ADPSQ FELLK V LG Q G S YG KVFLVRK V T G SDA G Q L YA M KV L K K A TL KV R D A001562_Msk1 32 RTANLT G HAE K VGI E N FELLK V LGTGAYG KVFLVRK I S G HDA G K L YA M KV L K K A TI VQ K A A001298_Jnk3 48 FYSVEV G DSTFTVLKR Y QN LK P IGSGA Q G ------ IV C AA YD A V L DRN VAI K KLS RPFQN A001296_Jnk1 10 FYSVEI G DSTFTVLKR Y QN LK P IGSGA Q G ------ IV C AA YD A I L ERN VAI K KLS RPFQN A001454_Map4k3 1 -MNPGFDLSR R NPQ E D FELI QR IGSG T YG ------D V YK A RNVNTGE L A AI K V I K L EPGE A001144_Hpk1 1 MALVDPDIFN K DPR E H YDLL QR LG G G T YG ------E V FK A RDKVSKD LVAL K M V K M EPDD A001506_Mek2 56 AFLTQK A KVGELKD D D FE R I SE LG A G NG G ------ VV TK A RHRPSGF IMA R K L I H L EI K P A001561_Mrcka 61 KPFTSKVKQM R LHR E D FEILK V IG R GAFG ---EVA VV KLKNADK V FA M KI L N K WE M LK R A ( K72 in PKA) <--- C------> <- 4-> <- 5-> <--- D---> A002101_Rsk3 103 R--V R SKM E RD IL AEVN- HP F IV K LH Y AF QT E G KLYL I LDF LR GGDL FTR---LSKEVMF A001562_Msk1 92 K T TE H TRT E RQ VL EHIR Q S P F LV T LH Y AF QT E T KL H L I
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This note was uploaded on 10/05/2009 for the course BIBC 100 taught by Professor Nehring during the Winter '07 term at UCSD.

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Lect5 - Protein Kinase Domain Alignments (all of the N...

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