Lecture 4-2 Section Week 3

Lecture 4-2 Section Week 3 - Section week 3 Sleep on the...

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Sleep on the Brain: Sleep on the Brain: More on Why More on Why (some brainy sleep theories) (some brainy sleep theories) & How & How (brain mechanisms) (brain mechanisms) Based on lectures 2-4 Section - week 3
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Not all sleep is the same, right? Not all sleep is the same, right? Awake Stage 2 NREM Stage 4 NREM (SWS) REM Section - week 3
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So why do we spend a third So why do we spend a third of our lives asleep? of our lives asleep? Section - week 3
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Some (brainy) sleep theories Some (brainy) sleep theories Non-REM Repairs damaged brain cells Evidence: Small animals sleep more • Higher metabolic rates more free-radical damage • During NREM, metabolism slows, brain temp -- better conditions for cell repair Sleep deprivation (in rats) brain cell damage Section - week 3
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Some (brainy) sleep theories Some (brainy) sleep theories REM Restores monoamine receptor sensitivity Evidence: Constant monoamine release desensitizes receptors During REM, monoamine release ceases • Allows receptors to rest? • Restored sensitivity for mood regulation when awake? • Prevents long-term rewiring from REM’s higher brain activity? Section - week 3 Non-REM Repairs damaged brain cells
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Some (brainy) sleep theories Some (brainy) sleep theories REM Restores monoamine receptor sensitivity Neurodevelopment Evidence: REM highest early in life; reduces by adulthood More REM in species born developmentally immature Cats deprived of REM shortly after birth develop abnormal visual systems Section - week 3
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Lecture 4-2 Section Week 3 - Section week 3 Sleep on the...

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