prob set 6

prob set 6 - Problem Set 6 Genetics 411 1) Individual...

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Problem Set 6 Genetics 411 1) Individual chromosomes may differ in the number of minisatellite repeats present at a particular location along the chromosome. Cleavage on either side of the repeats generates restriction fragments that differ in length. Using the technique of DNA fingerprinting variability in minisatellite repeat numbers can be used to determine chromosomal identity. Due to an unfortunate event at the local Ames hospital, the identity of two new born baby boys was questioned. Individual Minisatellite DNA containing fragment Agarose gel lane Child A > > > #1 > > > > > Parental Set #1 Mom > > > #2 > > > > > Dad > > #3 > > Lane: #1 #2 #3 __ __ __ __ __ Given the polymorphic pattern created by variation in the number of minisatellite DNA repeats as characterized above could parental set #1 be the parents of child A ? (circle): YES or NO and WHY? 2) Minisatellite repeats are found throughout the human genome and are highly polymorphic between individuals. Many polymorphic minisatellite repeats have been mapped near genes associated with human disease. Consider a family in which one
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This note was uploaded on 10/07/2009 for the course GEN 409 taught by Professor Linda during the Fall '09 term at Iowa State.

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prob set 6 - Problem Set 6 Genetics 411 1) Individual...

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