16 - HMQC - Correlating more spins: H and X (1H and 13C,...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Correlating more spins: H and X ( 1 H and 13 C, e.g.) We have seen 1 H- 1 H correlation (correlation spectroscopy-COSY). Now, we will connect our proton spectrum with its 13 C spectrum. This experiment, along with other data, is an important and powerful technique in the assignment ( 1 H and 13 C) of resonances and the elucidation of structure. One-bond correlations: HMQC and HSQC (H eteronuclear M ulitiple Q uantum C oherence) (H eteronuclear Single Quantum C oherence) The ability to correlate the proton spectrum with its carbon-13 spectrum allows you add new pieces to your spectroscopy puzzle. For example, if you know you have a CH 2 (because of a DEPT experiment), you now can connect the proton resonance(s) with its directly bonded carbon. You will also know when two different 1 H signals are correlated to a single carbon (in the case of diastereotopic 1 H’s).
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 The important experiments Sensitivity gains of the inverse (proton) detected experiments (and where is the magnetization during the experiment?):
Background image of page 2
3 An HMQC of menthol (at 500 MHz) The pulse sequence and the coherence-transfer pathways
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4 What are those diagrams about? (a small digression)
Background image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 10/08/2009 for the course CHEM 439 taught by Professor Falzone,c during the Spring '08 term at Pennsylvania State University, University Park.

Page1 / 11

16 - HMQC - Correlating more spins: H and X (1H and 13C,...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online