actin cytoskeleton

actin cytoskeleton - THE ACTIN CYTOSKELETON CHAPTER 17...

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THE ACTIN CYTOSKELETON CHAPTER 17 LECTURE 18
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4. Actin Microfilaments - General Characteristics * Helical polymers of actin protein; two protofilaments * Seven nanometers in diameter * Structurally polar; plus and minus end * Thinner, shorter and more flexible than microtubules; the total length of all actin filaments in most cells is ~ 30x's that of microtubules * Globular actin (G-actin) is basic subunit, highly conserved * In most cases fast reactions to stimuli * Located throughout cell in many arrangements, most highly concentrated in the cell's cortex * Actin filaments found primarily in linear bundles, two-dimensional (sheets, bundles) and three-dimension (gels) networks; rarely occur in isolation
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Microvilli Stress fibers Lamellipodia, Filopodia Contractile ring
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- Mechanisms of Polymerization and Depolymerization * Similar strategy as microtubules * Nucleotide (ATP) exchange/hydrolysis cycle * ATP cap * Microfilament organizing centers small, distributed, modular
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- Actin Binding Proteins Modify Behavior
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- Actin Binding Proteins Modify Behavior
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This note was uploaded on 10/10/2009 for the course BIO 351 taught by Professor Oberstein during the Spring '08 term at ASU.

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actin cytoskeleton - THE ACTIN CYTOSKELETON CHAPTER 17...

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