Lect-2-SV - Lecture 2 Recap A little chemistry helps to understand a lot of biology Covalent Bonds Polar and Non-Polar Electronegativity is key

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1 Recap: A little chemistry helps to understand a lot of biology Covalent Bonds 09-29-09: Lecture 2 Polar and Non-Polar Non-covalent bonds: Hydrogen Bonds Ionic Bonds Van der Waals Attraction Hydrophobic Effect Electronegativity is key! Acid base chemistry going on inside the cell Most small molecules and larger biomolecules have functional groups that can act as weak acids and bases Intra and inter molecular interactions intramolecular intermolecular
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2 Recap: A little chemistry helps to understand a lot of biology Biology is the interplay between covalent and non-covalent chemistry Molecule Cell 09-29-09: Lecture 2
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3 What is the importance of Molecular Shape and Function? Ex. Morphine has similar shape to endorphins – therefore it activates endorphin receptors similarly! 09-29-09: Lecture 2
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4 Why is carbon key to molecular shape and function? Carbon Chemistry C has 4e- in its outer shell, can form 4 different bonds - tetravalence 09-29-09: Lecture 2
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5 Why is carbon key to molecular shape and function? Carbon Chemistry Carbon skeletons can vary in length, branching, double bonds and rings – leads to diversity! 09-29-09: Lecture 2
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6 Carbon Chemistry Isomers Same number of atoms – but different structures Structural isomers 3 variations - pentane (C 5 H 12 ) 18 possibilities of C 8 H 18 366,319 possibilities of C 20 H 42 Geometric isomers cis and trans isomers Why is carbon key to molecular shape and function? 09-29-09: Lecture 2
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7 Carbon Chemistry Geometric isomers cis and trans isomers 11 – cis - retinal is found photoreceptor cells to transduce light signals from the eye to the brain
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This note was uploaded on 10/11/2009 for the course BILD 1 taught by Professor Kiger during the Spring '09 term at CSU Northridge.

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Lect-2-SV - Lecture 2 Recap A little chemistry helps to understand a lot of biology Covalent Bonds Polar and Non-Polar Electronegativity is key

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