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Unformatted text preview: Bis 104 Lecture 5 10/08 c. Ion channels in nerve cells * A typical vertebrate neuron Signals/feelings are transmitted along the nerve axon as a local changes in the membrane potential: action potential (nerve impulse) @ 10m/sec i. Membrane depolarizationi triggers action potential Channels has three states: closed, inactivated, open than closed again ii. Synapses: site of the transmission of neuronal signals from cell to cell *Example: A motor neuron cell body in the spinal cord *Signal transmission upon the arrival of the nerve impulse (action potential): At presynaptice membrane: 1) Open the voltage-gated Ca2+ channel 2) Trigger vesicle fusion (exocytosis) 3) Release neurotransmitter: electrical signal chemical signal At postsynaptic membrane 1) Open transmitter-gated channel: ion flow 2) Change membrane potential 3) Fire action potential: chemical signal electrical signal Q: In this particular micrograph, which type of microscopy was used, and what kind of resolution does it...
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- Spring '09