Gas%20Exchange%20Figs%20BW

Gas%20Exchange%20Figs%20BW - 1. Translucent left lung space...

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Outline A. Introduction C. Regulation of Breathing D. Transport of O 2 and CO 2 Gas Exchange
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Some Things to Remember About Gases Gas molecules move by diffusion Air is a mixture of gases: ~ 78 % Nitrogen ~ 21 % Oxygen ~ 1-3 % Carbon Dioxide variable levels of H 2 O Under standard conditions, air pressure is 760 mm Hg For any gas, express concentration as Partial Pressure = Total P x Fraction of Total P O2 = 760 mm Hg x 0.21 = 160 mm Hg
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Common Features of Respiratory Organs Respiratory surfaces are always wet Respiratory organs have a large surface area covered by a very thin epithelium Blood is brought very close to the respiratory surface O 2 -carrying capacity of blood is often enhanced by respiratory pigments
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Human Lung
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Human Lung: A Closer Look Epithelial cells secrete surfactant
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Breathing Movements * * intercostal muscles
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Emphysema / Pneumothorax 1. A-P chest size 2. Depressed diaphragm 3. Air space behind sternum
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Unformatted text preview: 1. Translucent left lung space 2. Collapsed left lung L R Source: http://web.indstate.edu/thcme/micro/respiratory/pnmothrx.gif P CO2 and pH Regulate Breathing CO 2 + H 2 O ' H 2 CO 3 ' H + + HCO 3- Metabolism P CO2 , pH Brain Stem Respiratory Center Respiratory Rate P O2 Transport of O 2 and CO 2 Hemoglobin O 2 Dissociation Curve Percent Saturation of Hb with O 2 100 P O2 (mm Hg) 40 100 Tissue Lung Hemoglobin Decreased Affinity ( PCO2, pH) Increased Affinity ( Temperature) DPG = 2,3-diphosphoglycerate Hemoglobin Also Transports CO 2 CO 2 + H 2 O ' H 2 CO 3 ' H + + HCO 3-Where is the CO 2 in the blood ? ~ 7 % is dissolved in plasma ~ 23 % is bound to amino groups (-NH 2 ) on hemoglobin* ~ 70 % exists as HCO 3-Excess H + binds to hemoglobin, so doesnt affect pH. amino acid N H H + C O O + H + * C O O amino acid N H...
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Gas%20Exchange%20Figs%20BW - 1. Translucent left lung space...

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