LectureOct7

LectureOct7 - BME 423 Lecture Notes - Oct. 7, 2009 I....

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1 BME 423 Lecture Notes - Oct. 7, 2009 II. Types of Error in Inferences and Power of a Statistical Test A. The Idea B. Two Types of Errors C. What Determines a Test’s Power 1. Size of Type I Error 2. Size of Treatment Effect Glantz p 179-204 A. Trial Types B. Relative Risk C. Odds Ratio I. Association Between Nominal Variables - Review Glantz p 163-170 I. Association Between Nominal Variables Clinical Trials Patients are randomized to treatment groups and then the outcome is observed. Studies are prospective. e.g., treatment groups: aspirin vs. placebo observed outcome: thrombosis/no thrombosis A. Clinical Trials vs Epidemiological Studies
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2 Epidemiological Studies Group is determined by exposure to risk factor. 1) Prospective (cohort ) – Enrolled in study then followed over time to determine outcome. 2) Retrospective (case-control ) – People who have the outcome are identified/enrolled. Similarly, controls who do not have the outcome are identified/enrolled.
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LectureOct7 - BME 423 Lecture Notes - Oct. 7, 2009 I....

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