VSC433 Exam 1 F08 KEY - VSC/MIC/MCB 433 Medical and...

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VSC/MIC/MCB 433 Medical and Molecular Virology Fall 2008 Exam One Part 1. Multiple Choice: 2 points each. Enter your answers on the Scantron sheet. You can keep this part of the exam, so you may want to circle your answers on this too . 1. At the vertex of an icosahedron there exists 5-fold symmetry. a) True b) False 2) A pseudoknot is a secondary structure in viral RNA which has as function(s).: a) Causes frameshifting b) Allows for internal ribosomal entry c) Is complementary to the sgRNA d) Aids in membrane fusion e) Both a and b 3) Viral, as opposed to cellular, membrane fusion involves: a) The aggregation of clathrin b) Insertion of a fusion peptide c) The formation of an endosome d) Conformational changes of the membrane due to low pH 4) All viral infections cause disease. a) True b) False 5) Which DNA virus does NOT travel to the nucleus and carries its own RNA POL II? a) Adeno b) Polio c) Pox d) Herpes e) Retrovirus 6) In the one step growth curve, the eclipse phase in which the virus count drops to near zero, what is happening? a) The infected cells are being lysed and dying b) The immune response is killing the virus c) Virus death equals virus formation d) The virus is unable to enter the cell e) The viruses are inside the cells, beginning syntheses
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7) In HIV, the virus attaches to the cellular CD4 receptor and then CCR5, which it has high affinity for, and which pulls it closer to the cell. CCR5 is an example of: a) Accessory receptor b) Coreceptor c) Allosteric binding site d) Active site e) Primary receptor 8) Which of the following is True of ALL viruses: a) Have one piece of genome b) Have a narrow host range c) Have protein envelopes d) Have icosahedron symmetry e) Are obligately intracellular 9) _________ can go straight to the ribosome upon entering the cell. a) dsDNA
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This note was uploaded on 10/17/2009 for the course VSC 433 taught by Professor Dr.jimcollins during the Fall '08 term at University of Arizona- Tucson.

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VSC433 Exam 1 F08 KEY - VSC/MIC/MCB 433 Medical and...

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