VSC433 Exam 4 F08 KEY - Name:_ VSC/MIC/MCB 433 Medical and...

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Name:_____________________ VSC/MIC/MCB 433 Medical and Molecular Virology Fall 2008, Exam Four Multiple Choice and True False. Choose the best answer. One point each 1. What function does reverse transcriptase serve for retroviruses? a. ssRNA -> dsDNA b. ssRNA -> cdsDNA c. dsRNA -> ssDNA d. dsRNA -> dsDNA e. ssRNA -> ssDNA 2. Which of the following does not have DNA in its life cycle? a. Rotavirus b. Adenovirus c. Herpesvirus d. Human Immunodeficiency Virus e. a and d 3. All of the following use reverse transcriptase EXCEPT: a. Retroviruses b. Lentiviruses c. Spumaviruses d. Adenoviruses e. retrotransposons 4. Which of the following are not infectious by themselves i.e. do not need a concurrent infection? a. Avian Leukemia Virus b. Murine (Mouse) Sarcoma Virus c. Hepatitis D d. HIV e. both b and c 5. Which of the following Human Herpes Viruses does not become latent in the nerve cells? a. Herpes Simplex Type-1 b. Varicella Zoster c. Herpes Simplex Type-2 d. Epstein Barr Virus e. None of the above 6. Which of the following viruses is not tumorgenic? a. Papilloma b. Epstein Barr Virus
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c. Hepatitis C d. Polyoma e. All of the Above 7. Which of the following is not a reproduction strategy of DNA viruses? a. Bring own replication machinery b. Replicate in actively replicating cells c. Induce cellular replication e. All of the above are strategies d. None of the above 8. Which of the following does not use the cellular RNA POL II to replicate their genomic RNA? a. Viroids b. Prions c. Hepatitis D d. HIV d. All of the above use RNA POL II 9. Which of the following viruses replicate in the cytoplasm? a. Herpes virus b. Pox Virus c. Adeno Virus d. Polyoma virus e. All of the above replicate in the nuclueus 10. Circoviruses would most likely replicate via which DNA virus “strategy”? a. Stimulate the host cell to enter S phase. b. Include genes required for replication within its own genome. c. Replicate in the cytoplasm. d. Use the host cell machinery in cells already dividing. 11. UNLIKE the genome of retroviruses, the provirus: a. Is dsDNA b. is flanked by LTR’s on either side c. has gag, pol, and env d. all of the above e. both a and b 12. The first jump the polymerase makes in making DNA from RNA in retroviruses occurs after: a. The entire minus DNA strand has been made, so that it can make the positive b. The entire positive DNA strand has been made, so that it can make the negative 2
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c. After the 5’ end DNA copy has been made and RNase removes the hybridized RNA d. After both DNA strands have been extended and completed e. None of the above 13. Which epidermal cell layer does papilloma virus infect in order to eventually replicate
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VSC433 Exam 4 F08 KEY - Name:_ VSC/MIC/MCB 433 Medical and...

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