BICD 100_-_HW 1 (PDF)

BICD 100_-_HW 1 (PDF) - Name Genetics Homework 1 Due in...

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Unformatted text preview: Name: ____________________________________ Genetics Homework 1 Due in lecture Wednesday, October 7 WebCT ID: ___________________________ UCSD ID: ___________________________ Please print out this document. Either type or write your answers. 1. Describe the levels of compaction needed to go from a double helix of DNA to a fully condensed mitotic chromosome. 2. A double‐stranded DNA molecule is 1 cm long, and the percentage of adenine is 15%. How many cytosines would be found in the DNA molecule? 3. Within a protein, certain amino acids are positively charged (e.g., lysine and arginine), some are negatively charged (e.g., glutamate and aspartate), some are polar but uncharged, and some are nonpolar. If you knew that a DNA‐ binding protein was recognizing the DNA backbone rather than base sequences, which amino acids in the protein would be good candidates for interacting with the DNA? 4. Like DNA, molecules of RNA contain large amounts of phosphorus. When Hershey and Chase grew their T2 phage in bacterial cells in the presence of radioactive phosphorus, the RNA must have also incorporated the label, and yet the experiment was not compromised. Why not? 5. Discuss the strengths and weaknesses of the three experiments that we discussed in lecture that led to the conclusion that DNA is the genetic material (Griffith, Avery et al, Hershey and Chase). Which experimental approach did you find the most convincing? Why? ...
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