BMB 402H - Chapter 26 Pathways Map Handout (Scanned)

BMB 402H - Chapter 26 Pathways Map Handout (Scanned) -...

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Unformatted text preview: firuwms ur' PURINE METABOLISM RNA DNA lDfA EFA de novo pathway ribose 5—phosphate dATP ATP lg ATP GTP dGTP BaieP;PSugar I AMP q; 0) .8 EB (CDXDP TS. (d)XDP 5-phophoribosyl—l—pyrophosphate m a) (CDXDP E a: (CUXDP SEC 82 (PRPP) 8§( O H q) H . . g & (d)XTP g x (d)XTP ‘ l glutamme g g (d)XTP j x (d)XTP u 9.. :3 m glutamate .3 F” a a :I H c: -H _‘ . _ _ . . ~ 1:: *u NADP+ NADPH ru 5 phosphoribosyl l amlne a S NADPH NADP+ 'u é—-—-"‘-/—-—‘—- P \L GDP _\—j . dGDP Base + Sugar dADP ribogucéeotideAD ‘1, 3 ribonucleoti e + PP ' re uc age ,1.“ ,9 reductase s s 4' M 3 r; ((3 ATP 3‘1 (03 ATP 4’ 303 ATP "gig ATP 5:: c: c: c: '3 g E GDP+Pi ‘ Glutamine lutamate a '3‘ ‘V “3 ASP+GTP \l NAD+ NADH +ATP AMP+PP1 °° ‘1' \J U. I , dAM]? AMPé—-Ad n losuccmatef-IMP'r—TM tudGMP Base. + Sugar -7_,__ a (u dehydrogenas ‘3 + P a, 'Eflenylafl I m g g 34‘ 2 53 m Egggfsga * 3:3 3 3 8 ‘5" c.‘ c: C m 0 cu SUE, pp: 1-4 m o 3 0 *4 ATP c a r: ‘ magma“: mu 3 .3 g & '3 '3 :3 3 32' K Cfgé ( 845 a a g \‘ u “ '-nuc e e “3—: -I -..| .c: ‘0 E [:5 a)? In if" Dc dAdenosine m E Adenosine a enosule .fi ; Inosine Xanthosine Guanosinef‘g’ dGuanosine Base + Sugar m '{j T deaminase g J m g Du o co m a) u) :1 0) ad 4:: I m m m and: ‘3‘ % my “a’ 3‘. mi": é’ .14“ :53 ° aw“ H :a' 33 P1 'U r .53 Pg. WY‘Le/flohde’ & 4-I ~H.G C do 0 ,c m a) $483 ribose 1-938“ 5.3 '5. ‘éfi I: m Nfiém o 3—H!) ’ 5 u m «a 5-: H a oil—1.1:: ‘ ago a: o Mu g m ‘3‘ xanthine as“ 1'3 '3. a 'U adenine 4:13-21 -d' ~--s guanine p, m \/ deaminase .0X1 ase deaminase .c: dInosine Adenine —-———) Hypoxanthlne—>Xanthine (—— Guanine Base ‘ Jflvcanthineox.dal ‘ ’h Esme Much;ng ghoflgkflm I Uric Acid 1 86 Biochemistry 402 H Spring PATHWAYS 0F PYRIMIDZEBIE METABOLISM ‘ Gad, v“ a . ACT? Jeammas‘e C E. ¢° ") (ch? 206 RNA . RNA l T G1utamate+ G1utamine+ATP 4 ADP + Pi D DNA Sase+Sugar l T dC'I‘P CTP é—‘——-———-———— UTP P dTTP ~ ' a) cu (d)XDP - (d)XDP d)XDP a, (d)XDPI? 3353 (d)XDP ‘ to mac d~ m I: de novo pathway peg ) fipad o H C ) d XTP d XTP d X (9.34 d XTP (0mm) ( ) g1utamine+2ATP+Hco3' ( ) E. ( r; a 3-H 333345118?” ‘ .. .- ribonuc leo tide d ‘3 “d '1' PP (—-—-—-——-— CDP 2ADP+Pi UDP UDP dTDP dCDPrlbogucleotidem . 3], re ‘1‘: age A , 4% 2‘; re UCtase m ‘ V V V. _" ‘h drofolate . cu AD ' y 5- G g ADP carban‘luoyl phosphate ' P reduetase TE ‘5 x A 4» 4s a x m \M ATP «3 «and ~ --- ~- methylfne g gt: 4:; :3 3‘ t'ilSPElT-‘télte E tetrah o— dihy rofolate Base+Sugar c“ 4" U 5 fola ‘ g + P dCMP N—carbamoylaspartate99—> UMP dUMP WdTMP s t ase 71(1/ 8 OJ cu g ADP | W a, ADP wag, -H (I! F: .H c: 0 Id 3 g '3 'C’ H a) 4:9 u .H n—I ",1 ATP 3 2 ATP 3'“ ’3 dCMP deaminase 3 “U 4: n u a u "‘ B 32a? dCytidine Cytidine W Uridine dUridine dThymidine 1 ‘1’ ° a) «5 Pi #w C m m ,‘j g '3, fig .4 deoxyribose-l-f dCytidine deaminase '5’ ‘9‘ "' '5 o. H phosphate Base. Cytosine w Uracil Thymine cytosine deminase J, Phosphorylase l adwtg; RNA 1’ W») m“ FQJUC'LMQ. ram kmumiwelycv W B—Alanine 6-Aminoisobutyric Acid °"‘"‘ r ! DNA, e-Volukmn) Mwavlau WWW “ ...
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This note was uploaded on 10/19/2009 for the course B M B 402H taught by Professor Kao during the Spring '09 term at Pennsylvania State University, University Park.

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BMB 402H - Chapter 26 Pathways Map Handout (Scanned) -...

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