1 - lec24hili - o What is meant by and adult stem cell?...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Intro to Development Highlights Mammalian development o Early events What is compaction? What is blastocyst? and how is it formed? Outer cells give rise to? Inner cell mass gives rise to? o Gastrulation Name germ layers and examples of tissues and organs each will form o Be able to discuss difference between determined and differentiated. o what are the major determination events during embryogenesis? What is a stem cell? o Define toti-, pluri-, multi- and uni- potent and be able to give examples. o Where would you find a toti-potent cell? o Name the point in development where totipotency is lost. o Name the point in development where pluripotency is thought to be lost. Note that this wording “Lost” implies that this is irreversible. Is this true?
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: o What is meant by and adult stem cell? (e.g., what is the source of the stem cells?) What is HSC? o What is ES? Presumably ES cells are pluripotent. How is this demonstrated for mouse ES cells and why cant this be formally proven for human? How do we determine a human stem cell line is multipotent?- differentiate into different types of cells in culture is one way What are the sources of ES cells? Human ES cell source ? donated embryos from in vitro fertilization procedures Human EG (embryonic germ stem cell) cell source ? pre-term fetus o How could stem cells be useful for a therapeutic purpose? What is SCNT? what is reprogramming? why is this potentially useful?...
View Full Document

This note was uploaded on 10/19/2009 for the course B M B 460 taught by Professor Hanna-rose,w during the Spring '08 term at Pennsylvania State University, University Park.

Ask a homework question - tutors are online