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bis_104_pq_5 - In addition to the differentiation markers...

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BIS 104 PQ 5 5. To further investigate the possible role of peripheral nerves in mouse limb skin arteriogenesis, Mukouyama made use of the Neurogenin 1 / Neurogenein 2 (Ngn1 / Ngn2) double homozygous mutant strain of mice. It had been established previously that these mice lack peripheral sensory nerves. Describe the experiments that Mukouyama did with these mice. What conclusion did he arrive at based on the results of these experiments?
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Unformatted text preview: In addition to the differentiation markers that you have encountered in experiments described in figs 1 – 3, figure 4 describes the expression of two additional markers; BFABP (brain fatty acid binding protein) and alpha-SMA (alpha-smooth muscle actin). What cell types are specifically identified by these two markers?...
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