bis_104_pq_10 - begin to express ephrinB2 and CX-40 on...

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BIS 104 PQ 10 10. When undifferentiated endothelial cells (ECs: PECAM-1 positive; ephrinB2 negative) are isolated and grown in cell culture for 3 days, they fail to differentiate. That is, they do not begin to express arterial EC markers such as ephrinB2 and CX-40 proteins. However, when these undifferentiated ECs are cultured in the presence of added Schwann cells for 2 – 3 days, the ECs
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Unformatted text preview: begin to express ephrinB2 and CX-40 on their plasma membranes. a) What experimental procedure would you use to detect the presence of these differentiation markers on EC membranes? b) Does this experimental result demonstrate plausibility, necessity, or sufficiency? Explain your answer and state the conclusion that can be drawn from this result....
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This note was uploaded on 10/20/2009 for the course BIS 104 taught by Professor Scholey during the Spring '08 term at UC Davis.

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